First edition. Signed by both authors without attribution on half-title page ('Sincerely, George Beadle, Muriel Beadle'). Faint abrasion on front board. 1966 Full-Leather. x, [4], 242, [4] pp. 8vo. Finely rebound by Sangorski & Sutcliffe in full beige morocco with gilt titles, rules, and decorations, all edges gilt, marbled endpapers. The collector who had these rebound included his/her monogram on the corner of the front board: O.C.S. A description of the science of genetics by George Beadle and his wife Muriel. George Beadle won the Nobel Prize in Physiology or Medicine for his work with Edward Tatum, which led to them discovering the role of genes in regulating biochemical events within cells in 1958. Their research led them to the 'one gene - one enzyme hypothesis'.